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The first commercial Sanger sequencing machine was produced that year by Applied Biosystems (ABS), which Hood had co-founded in 1981. Called the ABI 370A, it retailed for $92,500. Since Sanger never patented his method, other companies were free to develop competing products, and by 1988, there were three Sanger sequencing machines on the market. These were followed by numerous others, including the Perkin-Ellmer 3700, used by Celera and the Human Genome Project, and the ABS 3500 Genetic Analyzer, which is still found in many laboratories today.，这一点在搜狗输入法下载中也有详细论述
Top-left: Hourly patterns show late-night/early-morning commits have the highest vulnerability rates. Monthly patterns show April merge window peaks.，详情可参考safew官方版本下载
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